The brand new unstratified Kaplan–Meier estimators indicated that Os try as much as 72% one year just after directory hospitalization, coming down which have prolonged realize-up (61% during the 2-seasons and you may 37% in the 5-12 months pursue-up). Female CLTI people presented down emergency rates in contrast to male customers (Profile 1A and watch Second material online , Desk S4 ) as well as the impact the mortality was high in women try supported by new Kaplan–Meier contours alone of one's RF (come across Additional issue online , Contour S3A–D ). However,, if entire cohort was classified in numerous a long time (?39, 40–44, 50–59, 60–69, 70–79, 80–89, and you can ?90 ages), women CLTI clients displayed a low death rates in all decades communities (Figure 1B–H). Brand new Kaplan–Meier estimators of age- and you can RF-paired cohort presented highest mortality pricing for males (select Supplementary situation on the web , Desk S4 ). Moreover, nearly one-sixth undergone a keen amputation of LL in the first 12 months shortly after index hospitalization that have rising thinking and the probability getting amputation is actually lower in feminine CLTI customers weighed against men (get a hold of Additional point on the internet , Table S4 and you will Contour S3E–H ). The newest Kaplan–Meier estimators of combined endpoint of amputation of LL otherwise demise pertaining to 40% of one's customers, without having any major differences between the fresh sexes throughout step 1-season realize-up (select Secondary thing online , Desk S4 and you will Contour S3I–L ). להמשיך לקרוא New collective frequency quotes (enjoy cost) to possess passing
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